Micro-/nanometer rough structure of a superhydrophobic biodegradable coating by electrospraying for initial anti-bioadhesion

Changmin Hu; Shen Liu; Bin Li; Huilin Yang; Cunyi Fan; Wenguo Cui

doi:10.1002/adhm.201300021

Micro-/nanometer rough structure of a superhydrophobic biodegradable coating by electrospraying for initial anti-bioadhesion

Adv Healthc Mater. 2013 Oct;2(10):1314-21. doi: 10.1002/adhm.201300021. Epub 2013 Apr 2.

Authors

Changmin Hu¹, Shen Liu, Bin Li, Huilin Yang, Cunyi Fan, Wenguo Cui

Affiliation

¹ Department of Orthopedics, The First Affiliated Hospital of Soochow University, 188 Shizi Street, Suzhou, Jiangsu 215006, P. R. China and Orthopedic Institute, Soochow University, 708 Renmin Road, Suzhou, Jiangsu 215007, P. R. China.

PMID: 23554405
DOI: 10.1002/adhm.201300021

Abstract

A novel superhydrophobic biodegradable coating with micro-/nanometer rough structure, fabricated by co-electrospraying poly(L-lactide) (PLLA) and modified silica nanoparticles (MSNs), exhibits good anti-adhesion behavior towards bacteria and cells in the initial culturing phase, which makes it a promising technology for preparing medical device coatings.

Keywords: anti-adhesion; biodegradation; electrospraying; nanoparticles; superhydrophobic surfaces.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Bacterial Adhesion / drug effects
Biocompatible Materials / chemistry*
Biocompatible Materials / metabolism
Cell Adhesion / drug effects
Cell Line
Hydrophobic and Hydrophilic Interactions
Mice
Nanoparticles / chemistry*
Nanoparticles / toxicity
Particle Size
Polyesters / chemistry
Silicon Dioxide / chemistry
Staphylococcus aureus / physiology

Substances

Biocompatible Materials
Polyesters
poly(lactide)
Silicon Dioxide