Sequencing-based genome-wide association study in rice

Bin Han; Xuehui Huang

doi:10.1016/j.pbi.2013.03.006

Sequencing-based genome-wide association study in rice

Curr Opin Plant Biol. 2013 May;16(2):133-8. doi: 10.1016/j.pbi.2013.03.006. Epub 2013 Apr 4.

Authors

Bin Han¹, Xuehui Huang

Affiliation

¹ National Center for Gene Research, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200233, China. [email protected]

PMID: 23562592
DOI: 10.1016/j.pbi.2013.03.006

Abstract

Rice, which has a modest genome size, is a wonderful model crop that has been comprehensively studied in functional genomics. With vast germplasm resources and reduced sequencing cost, genome-wide association study (GWAS) has been feasible to explore the allelic variation underlying agronomic traits in rice. In this review, we firstly summarize the work on constructing GWAS platforms in human genetics and in Arabidopsis and maize, from which we have a lot to learn. We then discuss the sequencing strategies and experimental designs for GWAS of agronomic traits in rice, and the perspective and challenges coupled with GWAS work are further addressed.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Base Sequence
Genetic Variation
Genome-Wide Association Study*
Humans
Molecular Sequence Data
Oryza / genetics*
Phenotype
Sequence Analysis, DNA*