EMBO J (2013) 32 10, 1365–1380. doi:; DOI: 10.1038/emboj.2013.60
Long-term potentiation (LTP) of synaptic transmission has received widespread attention because it is thought to form the physiological basis of learning and memory. A new paper in The EMBO Journal identifies the atypical PKC family member PKCλ as an important contributor to the strengthening of the postsynaptic response in LTP.