A semi-automated computer tool for the analysis of retinal vessel diameter dynamics

Comput Biol Med. 2013 Jun;43(5):513-23. doi: 10.1016/j.compbiomed.2013.02.013. Epub 2013 Mar 20.

Abstract

Retinal vessels are directly accessible to clinical observation. This has numerous potential interests for medical investigations. Using the Retinal Vessel Analyzer, a dedicated eye fundus camera enabling dynamic, video-rate recording of micrometric changes of the diameter of retinal vessels, we developed a semi-automated computer tool that extracts the heart beat rate and pulse amplitude values from the records. The extracted data enabled us to show that there is a decreasing relationship between heart beat rate and pulse amplitude of arteries and veins. Such an approach will facilitate the modeling of hemodynamic interactions in small vessels.

MeSH terms

  • Adult
  • Artifacts
  • Diagnostic Techniques, Ophthalmological*
  • Heart Rate / physiology
  • Humans
  • Image Processing, Computer-Assisted / methods*
  • Linear Models
  • Retinal Vessels / anatomy & histology*
  • Retinal Vessels / physiology
  • Signal Processing, Computer-Assisted*
  • Video Recording