Malignant epithelioid hemangioendothelioma progressing after chemotherapy and Interferon treatment: a case presentation and a brief review of the literature

J Cancer Res Ther. 2013 Jan-Mar;9(1):125-7. doi: 10.4103/0973-1482.110386.

Abstract

Epithelioid hemangioendothelioma is a rare, low-grade malignant vascular tumour. It is frequently seen in the liver, but can occur in the lungs, bones, and other soft tissues. Although survival time might be reasonable in cases that can undergo liver transplantation, there is no consensus on the treatment of metastatic patients. We report a 24-year-old female patient with rapidly progressing malignant epithelioid hemangioendothelioma that presented with acute abdominal distension. The patient was refractory to anthracycline and Interferon treatment and died 6.5 months after the diagnosis.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Antigens, CD34 / metabolism
  • Antineoplastic Agents / therapeutic use
  • Disease Progression
  • Fatal Outcome
  • Female
  • Hemangioendothelioma, Epithelioid / diagnosis*
  • Hemangioendothelioma, Epithelioid / drug therapy
  • Humans
  • Immunohistochemistry
  • Interferons / therapeutic use
  • Intra-Abdominal Fat / metabolism
  • Intra-Abdominal Fat / pathology
  • Liver Neoplasms / diagnosis*
  • Liver Neoplasms / drug therapy
  • Platelet Endothelial Cell Adhesion Molecule-1 / metabolism
  • Tomography, X-Ray Computed
  • Young Adult

Substances

  • Antigens, CD34
  • Antineoplastic Agents
  • Platelet Endothelial Cell Adhesion Molecule-1
  • Interferons