Structure of the tetramerization domain of measles virus phosphoprotein

J Virol. 2013 Jun;87(12):7166-9. doi: 10.1128/JVI.00487-13. Epub 2013 Apr 10.

Abstract

The atomic structure of the stable tetramerization domain of the measles virus phosphoprotein shows a tight four-stranded coiled coil. Although at first sight similar to the tetramerization domain of the Sendai virus phosphoprotein, which has a hydrophilic interface, the measles virus domain has kinked helices that have a strongly hydrophobic interface and it lacks the additional N-terminal three helical bundles linking the long helices.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Magnetic Resonance Spectroscopy
  • Measles virus / chemistry*
  • Measles virus / metabolism
  • Models, Molecular
  • Molecular Sequence Data
  • Phosphoproteins / chemistry*
  • Protein Multimerization
  • Protein Structure, Secondary
  • Viral Proteins / chemistry*

Substances

  • Phosphoproteins
  • Viral Proteins

Associated data

  • PDB/3ZDO