Abstract
This article aims at presenting the interest of high dose rate brachytherapy in the radiation treatment of prostatic adenocarcinoma. We will discuss successively the biological and dosimetric specificity of brachytherapy for this particular cancer. Afterwards, we will review the main phase II and III studies, the therapeutic indications in the daily practice from the evidence based medicine as well as the techniques of external beam radiation therapy for the same indications. Finally, the principal avenues of development will be discussed.
Copyright © 2013 Société française de radiothérapie oncologique (SFRO). Published by Elsevier SAS. All rights reserved.
MeSH terms
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Adenocarcinoma / diagnostic imaging
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Adenocarcinoma / drug therapy
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Adenocarcinoma / pathology
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Adenocarcinoma / radiotherapy*
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Antineoplastic Agents, Hormonal / therapeutic use
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Brachytherapy / adverse effects
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Brachytherapy / methods*
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Clinical Trials, Phase II as Topic
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Clinical Trials, Phase III as Topic
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Combined Modality Therapy
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Evidence-Based Medicine
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Humans
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Male
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Prostatic Neoplasms / diagnostic imaging
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Prostatic Neoplasms / drug therapy
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Prostatic Neoplasms / pathology
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Prostatic Neoplasms / radiotherapy*
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Radiation Injuries / etiology
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Radiation Injuries / prevention & control
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Radiation Tolerance
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Radiometry
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Radiotherapy Dosage
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Radiotherapy Planning, Computer-Assisted
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Radiotherapy, Image-Guided
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Risk Assessment
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Ultrasonography
Substances
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Antineoplastic Agents, Hormonal