CPAP treatment has a great importance in the treatment of obstructive sleep apnea syndrome and preventing complications due to obstructive sleep apnea syndrome however if it is not used by the patients, there is no point to diagnose obstructive sleep apnea syndrome. In this review, we wanted to inform the physicians who meet with this kind of patients often in their daily practice about the compliance problems in patients who use CPAP and solution ways. That is why we presented compliance problems in subtitles such as treatment modalities, demographic properties of patients, severity of disease, clostrophobia, patient, physician, healthcare profesional.