Transmitted drug resistance in French HIV-2-infected patients

AIDS. 2013 Jun 19;27(10):1671-4. doi: 10.1097/QAD.0b013e32836207f3.

Abstract

We report the first transmitted drug resistance survey study in HIV-2-infected patients living in France. The prevalence of transmitted drug resistance was 5.0% (95% confidence interval, 0.1-9.9) with mutations detected only in protease, not in reverse transcriptase. In this series, 10% of patients displayed X4/dual-mixed viruses. These findings classified the rate of transmitted drug resistance in the HIV-2 French Cohort as low prevalence.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Drug Resistance, Viral / genetics*
  • France / epidemiology
  • HIV Infections / drug therapy
  • HIV Infections / epidemiology
  • HIV Infections / virology*
  • HIV Protease Inhibitors / pharmacology
  • HIV-2 / drug effects
  • HIV-2 / genetics*
  • Humans
  • Prevalence
  • RNA, Viral / genetics
  • Reverse Transcriptase Inhibitors / pharmacology

Substances

  • HIV Protease Inhibitors
  • RNA, Viral
  • Reverse Transcriptase Inhibitors