Acrophialophora fusispora brain abscess in a patient with acquired immunodeficiency syndrome: a case report and review of the literature

Chia-Wen Li; Hsin-Chun Lee; Tsung Chain Chang; Jau-Yn Wan; Hung-Mo Chen; Chi-Jung Wu; Nan-Yao Lee; Chia-Ming Chang; Ching-Chi Lee; Wen-Chien Ko

doi:10.1016/j.diagmicrobio.2013.03.016

Acrophialophora fusispora brain abscess in a patient with acquired immunodeficiency syndrome: a case report and review of the literature

Diagn Microbiol Infect Dis. 2013 Jul;76(3):368-71. doi: 10.1016/j.diagmicrobio.2013.03.016. Epub 2013 Apr 17.

Authors

Chia-Wen Li¹, Hsin-Chun Lee, Tsung Chain Chang, Jau-Yn Wan, Hung-Mo Chen, Chi-Jung Wu, Nan-Yao Lee, Chia-Ming Chang, Ching-Chi Lee, Wen-Chien Ko

Affiliation

¹ Division of Infectious Diseases, Department of Internal Medicine, National Cheng Kung University Hospital and Medical College, Tainan, Taiwan.

PMID: 23601455
DOI: 10.1016/j.diagmicrobio.2013.03.016

Abstract

We reported a fatal case of brain abscess caused by Acrophialophora fusispora in a patient with acquired immunodeficiency syndrome. Identification of the fungus was based on microscopic morphology and sequence analyses of the internal transcribed spacer 1 (ITS1) and 2 (ITS2) of ribosomal RNA gene from the isolate recovered from brain abscess. Four published cases were reviewed as well.

Publication types

Case Reports
Review

MeSH terms

Acquired Immunodeficiency Syndrome / complications*
Ascomycota / genetics
Ascomycota / isolation & purification*
Brain Abscess / diagnosis*
Brain Abscess / drug therapy
Brain Abscess / microbiology
Central Nervous System Fungal Infections / diagnosis*
Central Nervous System Fungal Infections / drug therapy
Central Nervous System Fungal Infections / microbiology
Fatal Outcome
Humans
Male
Middle Aged
Multilocus Sequence Typing
Mycological Typing Techniques