Anomalous origin of coronary arteries from a single sinus of Valsalva

Reports of incidental coronary artery abnormalities range from 0.6% to 1.3% during routine angiography, and 0.3% in autopsies. An isolated single coronary artery is a particularly rare congenital anomaly. Clinical presentation is usually nonspecific; patients with an isolated single coronary anomaly may present with symptoms such as angina, myocardial infarction or sudden cardiac death. The therapeutic options depend on origin, course and termination. It is dangerous and potentially lethal if a single coronary artery is associated with obstructive coronary artery disease. Two cases of anomalous origin of a coronary artery from a single Valsalva sinus without any other visible coronary artery detected by aortography are reported.