Surgical treatment of extraluminal pelvic recurrence from rectal cancer: oncological management and resection techniques

J Visc Surg. 2013 Apr;150(2):97-107. doi: 10.1016/j.jviscsurg.2013.03.007. Epub 2013 Apr 23.

Abstract

Local recurrence (LR) after curative surgery for rectal cancer occurs in 4 to 33% of cases especially with suboptimal surgery (non-TME). For numerous patients, diagnosis of LR is done at late stage of the disease because of the high rate of asymptomatic patients. MRI and PET-scan are the most performing exams to assess the local and general extension, with high diagnostic accuracy (sensibility 85% and specificity 92%). For extraluminal pelvic recurrences from rectal cancer, pelvic exenterations alone or with irradiation (preoperative and/or intraoperative) can afford a R0 resection rate ranging from 30% to 45% with acceptable morbidity. Morbidity and mortality rates are high for total exenteration and abdominosacral resection. After curative surgery, 5-year global survival from 30% to 40% is observed. Careful selection of patients with better preoperative status before resection is needed to achieve more curative resections and increase long-term survivor rates.

Publication types

  • Review

MeSH terms

  • Adenocarcinoma / diagnosis
  • Adenocarcinoma / mortality
  • Adenocarcinoma / surgery*
  • Adenocarcinoma / therapy
  • Combined Modality Therapy
  • Humans
  • Neoplasm Recurrence, Local / diagnosis
  • Neoplasm Recurrence, Local / mortality
  • Neoplasm Recurrence, Local / surgery*
  • Neoplasm Recurrence, Local / therapy
  • Palliative Care
  • Pelvic Exenteration
  • Pelvic Neoplasms / diagnosis
  • Pelvic Neoplasms / mortality
  • Pelvic Neoplasms / surgery*
  • Pelvic Neoplasms / therapy
  • Plastic Surgery Procedures
  • Quality of Life
  • Rectal Neoplasms / diagnosis
  • Rectal Neoplasms / mortality
  • Rectal Neoplasms / surgery*
  • Rectal Neoplasms / therapy
  • Rectum / surgery
  • Survival Rate
  • Treatment Outcome