Abstract
We describe a case of human tularemia caused by Francisella tularensis subsp. holarctica in a stem cell transplant recipient with chronic graft-versus-host disease who was receiving levofloxacin prophylaxis. The infection was characterized by pneumonia with septic complications. The patient was successfully treated with doxycycline.
Keywords:
Francisella tularensis ssp. holarctica; bacteria; chronic graft-versus-host disease; immunocompromised host; tularemia; vector-borne infections.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Anti-Bacterial Agents / therapeutic use*
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Chronic Disease
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Doxycycline / therapeutic use*
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Francisella tularensis / isolation & purification
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Graft vs Host Disease / complications
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Graft vs Host Disease / drug therapy*
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Graft vs Host Disease / microbiology
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Hematopoietic Stem Cell Transplantation*
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Humans
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Levofloxacin
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Male
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Middle Aged
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Ofloxacin / therapeutic use
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Pneumonia / complications
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Pneumonia / drug therapy*
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Pneumonia / microbiology
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Tularemia / complications
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Tularemia / drug therapy*
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Tularemia / microbiology
Substances
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Anti-Bacterial Agents
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Levofloxacin
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Ofloxacin
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Doxycycline