Serial measurements of high-sensitivity cardiac troponin T after exercise stress test in stable coronary artery disease

Biomarkers. 2013 Jun;18(4):304-9. doi: 10.3109/1354750X.2013.776635. Epub 2013 May 7.

Abstract

Objective: The aim was to assess serial measurements of high-sensitivity cardiac troponin T (hs-cTNT) post-exercise in patients with stable coronary artery disease (CAD).

Methods: Twelve patients with positive coronary angiograms (CAD positives) and 12 controls performed an exercise stress test.

Results: CAD positive had higher baseline and peak concentrations of hs-cTNT than controls. Significant increases in hs-cTNT were seen in both groups after exercise. In two-third of patients the peak in hs-cTNT was above the 99th percentile.

Conclusion: hs-cTNT is higher in patients with stable coronary disease than in controls and exceeds the diagnostic cut-off value for myocardial infarction in a majority of patients with CAD after exercise.

MeSH terms

  • Aged
  • Coronary Artery Disease / blood*
  • Coronary Artery Disease / physiopathology
  • Exercise Test*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Sensitivity and Specificity
  • Troponin T / blood*

Substances

  • Troponin T