PEGylated upconverting luminescent hollow nanospheres for drug delivery and in vivo imaging

Liang Dong; Duo An; Ming Gong; Yang Lu; Huai-Ling Gao; Yun-Jun Xu; Shu-Hong Yu

doi:10.1002/smll.201300433

PEGylated upconverting luminescent hollow nanospheres for drug delivery and in vivo imaging

Small. 2013 Oct 11;9(19):3235-41. doi: 10.1002/smll.201300433. Epub 2013 May 8.

Authors

Liang Dong¹, Duo An, Ming Gong, Yang Lu, Huai-Ling Gao, Yun-Jun Xu, Shu-Hong Yu

Affiliation

¹ Division of Nanomaterials & Chemistry, Hefei National Laboratory for Physical, Sciences at the Microscale, Department of Chemistry, University of Science and Technology of China, Hefei 230026, PR China.

PMID: 23657979
DOI: 10.1002/smll.201300433

Abstract

Upconversion luminescent hollow Y2 O3 :Yb(3+) /Er(3+) nanospheres can be synthesized by an etching-free process, which hold promising potential for applications such as drug delivery, angiography, and high-contrast cellular as well as tissue imaging, with no damage from radiation or toxicity.

Keywords: angiography; bioimaging; drug delivery; hollow nanospheres; upconversion; yttrium oxide.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Diagnostic Imaging / methods*
Drug Delivery Systems / methods*
Luminescence*
Nanospheres / chemistry*