TCF-1 mediates repression of Notch pathway in T lineage-committed early thymocytes

Blood. 2013 May 9;121(19):4008-9. doi: 10.1182/blood-2013-01-477349.
No abstract available

Publication types

  • Letter

MeSH terms

  • Animals
  • Cell Differentiation / genetics
  • Cell Lineage / genetics*
  • Cells, Cultured
  • Down-Regulation / genetics
  • Hepatocyte Nuclear Factor 1-alpha
  • Mice
  • Mice, Knockout
  • Receptors, Notch / genetics
  • Receptors, Notch / metabolism*
  • Signal Transduction / genetics
  • T Cell Transcription Factor 1 / genetics
  • T Cell Transcription Factor 1 / physiology*
  • T-Lymphocytes / metabolism*
  • T-Lymphocytes / physiology
  • Thymocytes / metabolism
  • Thymocytes / physiology*

Substances

  • Hepatocyte Nuclear Factor 1-alpha
  • Hnf1a protein, mouse
  • Receptors, Notch
  • T Cell Transcription Factor 1