Nipple reconstruction after implant-based breast reconstruction: a "matched-pair" outcome analysis focusing on the effects of radiotherapy

J Plast Reconstr Aesthet Surg. 2013 Sep;66(9):1202-5. doi: 10.1016/j.bjps.2013.04.052. Epub 2013 May 9.

Abstract

Background: The major focus of research when addressing nipple reconstruction has been on developing new techniques to provide for long-lasting nipple projection. Rarely, has the outcome of nipple reconstruction as it relates to postoperative morbidity, particularly after implant-based breast reconstruction, been analyzed.

Methods: A "matched-pair" study was designed to specifically answer the question whether a history of radiotherapy predisposes to a higher complication rate after nipple reconstruction in patients after implant-based breast reconstruction. Only patients with a history of unilateral radiotherapy who underwent bilateral mastectomy and implant-based breast reconstruction followed by bilateral nipple reconstruction were included in the study.

Results: A total of 17 patients (i.e. 34 nipple reconstructions) were identified who met inclusion criteria. The mean age of the study population was 43.5 years (range, 23-69). Complications were seen after a total of 8 nipple reconstructions (23.5 percent). Of these, 7 complications were seen on the irradiated side (41.2 percent) (p = 0.03).

Conclusion: While nipple reconstruction is a safe procedure after implant-based breast reconstruction in patients without a history of radiotherapy the presence of an irradiated field converts it to a procedure with a significant increase in postoperative complication rate.

Keywords: Breast reconstruction; Implant; Nipple reconstruction; Plastic surgery; Radiation.

Publication types

  • Comparative Study
  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Aged
  • Breast Implantation / adverse effects*
  • Breast Implantation / methods
  • Breast Implants*
  • Breast Neoplasms / radiotherapy
  • Breast Neoplasms / surgery
  • Case-Control Studies
  • Female
  • Follow-Up Studies
  • Humans
  • Mammaplasty / adverse effects
  • Mammaplasty / methods
  • Mastectomy / methods*
  • Middle Aged
  • Nipples / surgery*
  • Plastic Surgery Procedures / adverse effects
  • Plastic Surgery Procedures / methods
  • Postoperative Complications / etiology
  • Postoperative Complications / physiopathology
  • Radiotherapy Dosage
  • Radiotherapy, Adjuvant
  • Retrospective Studies
  • Risk Assessment
  • Surgical Flaps / blood supply*
  • Treatment Outcome
  • Young Adult