Abstract
Addition of neuroprotector Cortexin to standard drug therapy of patients with organic emotionally labile (asthenic) disorders had a great influence on the neuroendocrine system and neurosteroid content: normalization of blood concentration of cortisol, dehydroepiandrosterone sulphate, and thyroid hormones was observed. Clinical improvement was associated with the recovery of organism homeostatic systems.
Publication types
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Randomized Controlled Trial
MeSH terms
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Adult
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Affective Symptoms / drug therapy*
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Asthenia / drug therapy*
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Dehydroepiandrosterone Sulfate / blood
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Female
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Humans
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Hydrocortisone / blood
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Intercellular Signaling Peptides and Proteins
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Male
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Mood Disorders / drug therapy*
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Neuroprotective Agents / therapeutic use*
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Neurosecretory Systems / drug effects
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Peptides / therapeutic use*
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Thyroid Hormones / blood
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Treatment Outcome
Substances
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Intercellular Signaling Peptides and Proteins
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Neuroprotective Agents
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Peptides
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Thyroid Hormones
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Dehydroepiandrosterone Sulfate
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cortexin
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Hydrocortisone