Narcolepsy with obstructive sleep apnea in a 4-year-old Korean girl: a case report

J Korean Med Sci. 2013 May;28(5):792-4. doi: 10.3346/jkms.2013.28.5.792. Epub 2013 May 2.

Abstract

A 4-yr-old girl has exhibited severe snoring, restless sleep and increasing daytime sleepiness over the last 3 months. The physical examination showed that she was not obese but had kissing tonsils. Polysomnography demonstrated increased apnea-hypopnea index (AHI) of 5.2, and multiple sleep latency tests (MSLT) showed shortened mean sleep latency and one sleep-onset REM period (SOREMP). She was diagnosed with obstructive sleep apnea (OSA) and underwent tonsillectomy and adenoidectomy. After the surgery, her sleep became much calmer, but she was still sleepy. Another sleep test showed normal AHI of 0.2, the mean sleep latency of 8 min, and two SOREMPs. Diagnosis of OSA to be effectively treated by surgery and narcolepsy without cataplexy was confirmed. Since young children exhibiting both OSA and narcolepsy can fail to be diagnosed with the latter, it's desirable to conduct MSLT when they have severe daytime sleepiness or fail to get better even with good treatment.

Keywords: Children; Narcolepsy Without Cataplexy; Obstructive Sleep Apnea.

Publication types

  • Case Reports

MeSH terms

  • Adenoidectomy
  • Asian People
  • Child, Preschool
  • Disorders of Excessive Somnolence / diagnosis
  • Female
  • Humans
  • Methylphenidate / therapeutic use
  • Narcolepsy / complications
  • Narcolepsy / diagnosis*
  • Narcolepsy / surgery
  • Polysomnography
  • Republic of Korea
  • Sleep Apnea, Obstructive / diagnosis*
  • Sleep Apnea, Obstructive / drug therapy
  • Sleep Apnea, Obstructive / surgery
  • Tonsillectomy

Substances

  • Methylphenidate