Studies on production of fructo-oligosaccharides (FOS) by gamma radiation processing of microbial levan

Carbohydr Polym. 2013 Jul 1;96(1):365-70. doi: 10.1016/j.carbpol.2013.03.057. Epub 2013 Mar 26.

Abstract

Microbial levan, a natural polymer of fructose, was produced and purified by alcohol precipitation from culture supernatants of Bacillus megaterium type 1 grown in an optimized liquid sucrose medium. GPC analysis showed that the yield of the major fraction of levan having molecular weight ~5000 D increased with increase in sucrose concentration in the broth. Levan subjected to (60)Co-gamma radiation as well as acid hydrolysis was investigated by rheometry, UV-visible spectrophotometry and gel permeation chromatography (GPC) techniques. Unlike most of the polysaccharides, levan powder exhibited good radiation degradation stability up to 150 kGy. Gamma irradiation of 10% levan aqueous solution at 250 kGy yielded 63.0% fructo-oligosaccharide (FOS) with an average molecular weight of 1250 D. Acid hydrolysis of levan using 0.5 N HCl for 60 min treatment time gave rise to the desired FOS with lower yield (23.1%) as compared to that obtained in gamma radiolysis process.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacillus megaterium / metabolism*
  • Bacillus megaterium / radiation effects
  • Bacterial Load
  • Fructans / biosynthesis
  • Fructans / radiation effects*
  • Gamma Rays*
  • Oligosaccharides / chemistry*
  • Particle Size
  • Viscosity

Substances

  • Fructans
  • Oligosaccharides
  • levan