Linezolid resistance in Brazilian Staphylococcus hominis strains is associated with L3 and 23S rRNA ribosomal mutations

Antimicrob Agents Chemother. 2013 Aug;57(8):4082-3. doi: 10.1128/AAC.00437-13. Epub 2013 May 20.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acetamides / pharmacology*
  • Anti-Bacterial Agents / pharmacology
  • Bacterial Proteins / genetics
  • Bacterial Proteins / metabolism*
  • Brazil
  • Drug Resistance, Multiple, Bacterial
  • Genes, Bacterial
  • Humans
  • Intensive Care Units
  • Linezolid
  • Microbial Sensitivity Tests
  • Mutation*
  • Oxazolidinones / pharmacology*
  • RNA, Ribosomal, 23S / genetics
  • RNA, Ribosomal, 23S / metabolism*
  • Ribosomal Proteins / genetics
  • Ribosomal Proteins / metabolism*
  • Ribosomes / genetics
  • Ribosomes / metabolism
  • Staphylococcal Infections / diagnosis
  • Staphylococcus hominis / drug effects*
  • Staphylococcus hominis / genetics
  • Staphylococcus hominis / isolation & purification
  • Tertiary Care Centers

Substances

  • Acetamides
  • Anti-Bacterial Agents
  • Bacterial Proteins
  • L33 ribosomal protein, bacteria
  • Oxazolidinones
  • RNA, Ribosomal, 23S
  • Ribosomal Proteins
  • Linezolid