Correlations between echocardiographic aortic elastic properties and left ventricular rotation and twist--insights from the three-dimensional speckle-tracking echocardiographic MAGYAR-Healthy Study

Introduction: There is an interaction between the left ventricle (LV) and the vascular system, which plays a crucial role in determining cardiac output. LV twist could be evaluated by three-dimensional speckle-tracking echocardiography (3DSTE) as the net difference of counterclockwise apical and clockwise basal LV rotations during systole. Aortic elasticity parameters could be measured during a routine transthoracic echocardiographic examination. The current study was designed to evaluate correlations between echocardiographic aortic elastic properties and LV rotational mechanics in healthy subjects.

Methods: The present study comprised 26 healthy volunteers (mean age: 34.5 ± 9.8 years, 13 men). The following aortic elastic properties were measured from aortic data and forearm blood pressure values: aortic strain, distensibility and stiffness index (ASI). 3DSTE was used to measure basal and apical LV rotations and LV twist.

Results: During 3DSTE, basal LV rotation proved to be -2.42 ± 1.43 degree, while apical LV rotation was 8.56 ± 1.43 degree, therefore LV twist was 11.01 ± 5.19 degree. Aortic strain (0.131 ± 0.094), distensibility (3.61 ± 2.54 cm² dynes(-1) 10(-6)) and ASI (4.08 ± 0.79) were also calculated. Apical LV rotation correlated with aortic distensibility (r = -0.36, P<0.05) and ASI (r = 0.41, P<0.05). LV twist showed similar correlation with ASI (r = 0.42, P<0.05).

Discussion: Correlations exist between echocardiographic aortic elastic properties and 3DSTE-derived LV rotation and twist in healthy subjects.