Genome analysis of Staphylococcus aureus ST291, a double locus variant of ST398, reveals a distinct genetic lineage

PLoS One. 2013 May 21;8(5):e63008. doi: 10.1371/journal.pone.0063008. Print 2013.

Abstract

Staphylococcus aureus ST291 has been reported as a homologue recombinant double locus variant of the livestock associated S. aureus ST398. However, whole genome sequencing show that ST291 is a unique genetic lineage with highly variable content within its accessory genome compared to both human and livestock associated genome sequenced CC398s.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Base Sequence
  • Genetic Loci / genetics*
  • Genetic Variation
  • Genome, Bacterial / genetics*
  • Humans
  • Multilocus Sequence Typing
  • Phylogeny*
  • Sequence Analysis, DNA
  • Staphylococcus aureus / classification
  • Staphylococcus aureus / genetics*

Associated data

  • RefSeq/NC_002952

Grants and funding

The authors have no support or funding to report.