[Cerebral venous thrombosis: an unusual complication of acute cytomegalovirus infection]

Rev Med Interne. 2014 Apr;35(4):268-70. doi: 10.1016/j.revmed.2013.04.001. Epub 2013 May 21.
[Article in French]

Abstract

Introduction: Acute cytomegalovirus (CMV) infection increases the risk of vascular thrombosis but reports of cerebral venous thrombosis are rare.

Case report: We report a 36-year-old woman who presented with a cerebral venous thrombosis and acute CMV infection heralded by a cytolytic hepatitis. Heterozygous factor V Leiden mutation was also identified. The patient was treated with anticoagulation for 1 year with favourable outcome.

Conclusion: Serologic tests for CMV infection should be performed in case of cerebral venous thrombosis with liver cytolysis or flu-like symptoms. CMV infection often triggers thrombosis in combination with other inherited or genetic predisposing risk factors that should always be searched.

Keywords: Cerebral venous thrombosis; Cytolyse hépatique; Cytomegalovirus; Cytomégalovirus; Hepatitis; Thrombophlébite cérébrale.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Acute Disease
  • Adult
  • Cerebral Veins
  • Cytomegalovirus Infections / complications*
  • Cytomegalovirus Infections / diagnosis*
  • Cytomegalovirus Infections / genetics
  • Factor V / genetics
  • Female
  • Humans
  • Intracranial Thrombosis / diagnosis*
  • Intracranial Thrombosis / genetics
  • Intracranial Thrombosis / virology*
  • Mutation
  • Venous Thrombosis / diagnosis
  • Venous Thrombosis / genetics
  • Venous Thrombosis / virology

Substances

  • factor V Leiden
  • Factor V