Broad HPV distribution in the genital region of men from the HPV infection in men (HIM) study

Virology. 2013 Sep 1;443(2):214-7. doi: 10.1016/j.virol.2013.04.024. Epub 2013 May 28.

Abstract

The HPV infection in men (HIM) study examines the natural history of genital HPV infection in men. Genotyping methods used in this study identify 37 α-HPV types; however, the viral type could not be identified in approximately 22% of male genital specimens that were HPV PCR positive. Our aim was to genotype HPV-unclassified specimens by sequencing PGMY09/11, GP5+/6+ or FAP59/64 PCR products. Using this approach we were able to detect 86 unique HPV types among 508 of 931 specimens analyzed. We report for the first time the presence of a broad range of α-, β- and γ-HPV at the male genitals.

Keywords: Genera; Genital; Human papillomavirus; Men; Penile; Viral prevalence.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Brazil / epidemiology
  • DNA, Viral / analysis
  • DNA, Viral / genetics
  • Florida / epidemiology
  • Genitalia, Male / virology*
  • Genotype
  • Humans
  • Male
  • Mexico / epidemiology
  • Middle Aged
  • Papillomaviridae / classification*
  • Papillomaviridae / genetics
  • Papillomaviridae / isolation & purification*
  • Papillomavirus Infections / epidemiology*
  • Papillomavirus Infections / virology
  • Polymerase Chain Reaction / methods
  • Young Adult

Substances

  • DNA, Viral