Lytic and sclerotic (mixed) vertebral metastasis in ganglioneuroblastoma

Indian J Nucl Med. 2012 Apr;27(2):127-9. doi: 10.4103/0972-3919.110721.

Abstract

The clinical presentation of ganglioneuroblastoma is highly variable and it is not uncommon to see metastasis at presentation. Bone is the second most common site of metastasis in neuroblastoma. Neuroblastoma cells usually activate osteoclasts and form osteolytic lesions. Here, we describe a patient who presented with back pain. On evaluation, X-ray and positron emission tomography-computed tomography showed mixed lytic and sclerotic vertebral metastasis, and subsequently diagnosed as ganglioneuroblastoma.

Keywords: Ganglioneuroblastoma; metastasis; neuroblastoma; positron emission tomography-computed tomography.

Publication types

  • Case Reports