Temperature-responsive enzyme-polymer nanoconjugates with enhanced catalytic activities in organic media

Jingying Zhu; Yifei Zhang; Diannan Lu; Richard N Zare; Jun Ge; Zheng Liu

doi:10.1039/c3cc42493f

Temperature-responsive enzyme-polymer nanoconjugates with enhanced catalytic activities in organic media

Chem Commun (Camb). 2013 Jul 11;49(54):6090-2. doi: 10.1039/c3cc42493f.

Authors

Jingying Zhu¹, Yifei Zhang, Diannan Lu, Richard N Zare, Jun Ge, Zheng Liu

Affiliation

¹ Department of Chemical Engineering, Tsinghua University, Beijing 100084, PR China.

PMID: 23727906
DOI: 10.1039/c3cc42493f

Abstract

A general approach for preparing enzyme-polymer nanoconjugates that respond to temperature in organic media is presented. These nanoconjugates readily dissolve in organic solvents for homogenous catalysis at 40 °C and showed greatly enhanced apparent catalytic activities. The recovery of the soluble enzyme-polymer nanoconjugates is accomplished by temperature-induced precipitation.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Biocatalysis
Candida / enzymology
Enzymes, Immobilized / chemistry
Enzymes, Immobilized / metabolism
Hydrophobic and Hydrophilic Interactions
Lipase / chemistry*
Lipase / metabolism
Nanoconjugates / chemistry*
Poloxamer / chemistry
Polymers / chemistry*
Polypropylenes / chemistry
Solvents / chemistry
Temperature

Substances

Enzymes, Immobilized
Nanoconjugates
Polymers
Polypropylenes
Solvents
Poloxamer
Lipase