Abstract
The multiresistance gene cfr was identified for the first time in streptococci, namely, in porcine Streptococcus suis isolate S10. The cfr gene was detected on the ~100-kb plasmid pStrcfr, where it was bracketed by two copies of the novel insertion sequence ISEnfa5, located in the same orientation. The detection of a cfr- and ISEnfa5-containing amplicon by inverse PCR suggests that ISEnfa5 may play a role in the dissemination of cfr.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Animals
-
Bacterial Proteins / genetics
-
Bacterial Proteins / metabolism
-
Base Sequence
-
DNA Transposable Elements
-
Genes, Bacterial*
-
Genes, MDR*
-
Microbial Sensitivity Tests
-
Molecular Sequence Data
-
Plasmids / genetics
-
Plasmids / metabolism
-
Streptococcus suis / drug effects
-
Streptococcus suis / genetics*
-
Streptococcus suis / metabolism
-
Swine
-
Thiamphenicol / analogs & derivatives
-
Thiamphenicol / pharmacology
-
Transformation, Bacterial
Substances
-
Bacterial Proteins
-
DNA Transposable Elements
-
florfenicol
-
Thiamphenicol
Associated data
-
GENBANK/FJ660465
-
GENBANK/FR875178
-
RefSeq/NC_014508