Red flag imaging techniques in Barrett's esophagus

Payal Saxena; Marcia Irene Canto

doi:10.1016/j.giec.2013.03.002

Red flag imaging techniques in Barrett's esophagus

Gastrointest Endosc Clin N Am. 2013 Jul;23(3):535-47. doi: 10.1016/j.giec.2013.03.002. Epub 2013 May 3.

Authors

Payal Saxena¹, Marcia Irene Canto

Affiliation

¹ Division of Gastroenterology and Hepatology, Department of Medicine, The Johns Hopkins Medical Institutions, 1830 East Monument Street, Baltimore, MD 21287, USA.

PMID: 23735101
DOI: 10.1016/j.giec.2013.03.002

Abstract

The key to detection and treatment of early neoplasia in Barrett's esophagus (BE) is thorough and careful inspection of the Barrett's segment. The greatest role for red flag techniques is to help identify neoplastic lesions for targeted biopsy and therapy. High-definition white light endoscopy (HD-WLE) can potentially improve endoscopic imaging of BE compared with standard endoscopy, but little scientific evidence supports this. The addition of autofluorescence imaging to HD-WLE and narrow band imaging increases sensitivity and the false-positive rate without significantly improving overall detection of BE-related neoplasia.

Publication types

Review

MeSH terms

Acetic Acid
Adenocarcinoma / diagnosis*
Barrett Esophagus / diagnosis*
Early Detection of Cancer
Esophageal Neoplasms / diagnosis*
Esophagoscopy / methods*
Humans
Indicators and Reagents
Methylene Blue
Narrow Band Imaging / methods
Optical Imaging / methods*
Sensitivity and Specificity

Substances

Indicators and Reagents
Acetic Acid
Methylene Blue