Nanoparticles under the light: click functionalization by photochemical thiol-yne reaction, towards double click functionalization

Paul Demay-Drouhard; Emilie Nehlig; Julie Hardouin; Laurence Motte; Erwann Guénin

doi:10.1002/chem.201300903

Nanoparticles under the light: click functionalization by photochemical thiol-yne reaction, towards double click functionalization

Chemistry. 2013 Jun 24;19(26):8388-92. doi: 10.1002/chem.201300903. Epub 2013 Jun 6.

Authors

Paul Demay-Drouhard¹, Emilie Nehlig, Julie Hardouin, Laurence Motte, Erwann Guénin

Affiliation

¹ Université Paris 13, Sorbonne Paris Cité, Laboratoire CSPBAT, CNRS (UMR 7244), 74 Avenue M. Cachin 93017 Bobigny, France.

PMID: 23744751
DOI: 10.1002/chem.201300903

Abstract

A light click away: The first application of the thiol-yne reaction to nanoparticle functionalization is described (see figure). This metal-free click chemistry approach is compatible with the addition of various molecules at the surface and can be combined with CuAAC methodology to perform chemoselective double functionalization.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Alkynes / chemistry*
Click Chemistry
Ferric Compounds / chemistry
Nanoparticles / chemistry*
Sulfhydryl Compounds / chemistry*
Surface Properties
Ultraviolet Rays*

Substances

Alkynes
Ferric Compounds
Sulfhydryl Compounds
ferric oxide