The Rs of biology: R-loops and the regulation of regulators

Mol Cell. 2013 Jun 6;50(5):611-2. doi: 10.1016/j.molcel.2013.05.024.

Abstract

Work by Sun et al. (2013) in Arabidopsis reveals an additional function for R-loops in suppressing the expression of a long noncoding RNA and sheds light on the single-stranded DNA binding protein AtNDX that promotes persistence of the R-loop.

Publication types

  • Comment

MeSH terms

  • Arabidopsis / genetics*
  • Arabidopsis Proteins / genetics*
  • Arabidopsis Proteins / metabolism*
  • Homeodomain Proteins / metabolism*
  • MADS Domain Proteins / genetics*
  • RNA, Antisense / genetics*
  • RNA, Long Noncoding / genetics*
  • RNA, Plant / genetics*
  • Transcription, Genetic*

Substances

  • Arabidopsis Proteins
  • Homeodomain Proteins
  • MADS Domain Proteins
  • RNA, Antisense
  • RNA, Long Noncoding
  • RNA, Plant