Intraabdominal follicular dendritic cell sarcoma: a report of three cases and review of the literature

Tumori. 2013 Mar-Apr;99(2):e65-9. doi: 10.1177/030089161309900231.

Abstract

Follicular dendritic cell sarcoma (FDCS) is a rare neoplasm that originates from follicular dendritic cells in lymphoid follicles. FDCS has been increasingly reported in recent years. However, data on FDCS are mostly based on single case reports or case series and its natural history and standard treatment are not clear. To increase the understanding of this rare disease, we report our experience of three cases of FDCS with an analysis of the morphological and immunophenotypic characteristics, clinical course, treatment options and response to treatment. In addition, we reviewed the literature on FDCS.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Abdominal Pain / etiology
  • Adrenalectomy
  • Adult
  • Antineoplastic Combined Chemotherapy Protocols / administration & dosage
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Biomarkers, Tumor / analysis*
  • Chemotherapy, Adjuvant
  • Colostomy
  • Cyclophosphamide / administration & dosage
  • Dendritic Cell Sarcoma, Follicular / complications
  • Dendritic Cell Sarcoma, Follicular / diagnosis*
  • Dendritic Cell Sarcoma, Follicular / pathology
  • Dendritic Cell Sarcoma, Follicular / therapy*
  • Diagnosis, Differential
  • Epirubicin / administration & dosage
  • Female
  • Gastrointestinal Stromal Tumors / chemistry
  • Gastrointestinal Stromal Tumors / complications
  • Gastrointestinal Stromal Tumors / diagnosis*
  • Gastrointestinal Stromal Tumors / pathology
  • Gastrointestinal Stromal Tumors / therapy*
  • Humans
  • Immunohistochemistry
  • Immunophenotyping
  • Liver Neoplasms / chemistry
  • Liver Neoplasms / complications
  • Liver Neoplasms / diagnosis*
  • Liver Neoplasms / secondary
  • Liver Neoplasms / therapy*
  • Male
  • Melanoma / chemistry
  • Melanoma / complications
  • Melanoma / diagnosis*
  • Melanoma / pathology
  • Melanoma / therapy*
  • Melena / etiology
  • Middle Aged
  • Multimodal Imaging
  • Positron-Emission Tomography
  • Prednisone / administration & dosage
  • Proctoscopy
  • Rectal Neoplasms / chemistry
  • Rectal Neoplasms / complications
  • Rectal Neoplasms / diagnosis*
  • Rectal Neoplasms / pathology
  • Rectal Neoplasms / therapy*
  • Tomography, X-Ray Computed
  • Vincristine / administration & dosage

Substances

  • Biomarkers, Tumor
  • Epirubicin
  • Vincristine
  • Cyclophosphamide
  • Prednisone

Supplementary concepts

  • CEOP protocol 1