Bi2MoO6-RGO composite nanoplates with good uniformity and highly oriented growth of the active lattice were successfully synthesized by a simple hydrothermal process with the assistance of graphene oxide. Reduced graphene oxide was observed to be formed on the surface of the Bi2MoO6 nanoplates after the hydrothermal treatment. A remarkable enhancement in the visible-light-driven (VLD) photocatalytic destruction of bacteria was observed over the Bi2MoO6-RGO composite when compared to pure Bi2MoO6.