Abstract
Transcription-coupled repair (TCR) is one of the key of the nucleotide excision repair (NER) pathways required to preserve genome integrity. Although understanding TCR is still a major challenge, recent single-molecule experiments have brought new insights into the initial steps of TCR leading to new perspectives.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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DNA Damage / radiation effects
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DNA Helicases / metabolism
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DNA Repair*
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DNA-Directed RNA Polymerases / metabolism
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Escherichia coli / metabolism
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Escherichia coli Proteins / metabolism
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Protein Structure, Tertiary
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Transcription Factors / chemistry
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Transcription Factors / metabolism*
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Transcription, Genetic*
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Ultraviolet Rays
Substances
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Escherichia coli Proteins
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Transcription Factors
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DNA-Directed RNA Polymerases
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DNA Helicases