Abstract
Crohn's disease is associated with treatment and non-treatment infectious complications. Among the treatment-related infectious complications, Histoplasma infection is interesting because of significant overlap between its symptoms and Crohn's disease exacerbation. It is often mistaken as Crohn's disease exacerbation. We present a case of disseminated histoplasmosis presenting as Histoplasma epiglottitis in a patient with Crohn's disease maintained on infliximab, prednisone, and azathioprine.
Copyright © 2013 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.
MeSH terms
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Adult
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Antibodies, Monoclonal / adverse effects
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Antibodies, Monoclonal / therapeutic use
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Antifungal Agents / therapeutic use
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Azathioprine / adverse effects
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Azathioprine / therapeutic use
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Crohn Disease / complications*
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Crohn Disease / drug therapy
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Drug Therapy, Combination
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Epiglottitis / diagnosis
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Epiglottitis / drug therapy
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Epiglottitis / etiology*
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Histoplasma*
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Histoplasmosis / diagnosis
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Histoplasmosis / drug therapy
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Histoplasmosis / etiology*
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Humans
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Immunosuppressive Agents / administration & dosage
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Immunosuppressive Agents / adverse effects*
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Immunosuppressive Agents / therapeutic use
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Infliximab
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Male
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Prednisone / adverse effects
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Prednisone / therapeutic use
Substances
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Antibodies, Monoclonal
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Antifungal Agents
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Immunosuppressive Agents
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Infliximab
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Azathioprine
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Prednisone