Continuous G-CSF therapy for isolated chronic mucocutaneous candidiasis: complete clinical remission with restoration of IL-17 secretion

J Allergy Clin Immunol. 2013 Sep;132(3):761-764. doi: 10.1016/j.jaci.2013.04.018. Epub 2013 Jun 20.

Authors

Gizi Wildbaum¹, Eduardo Shahar², Rina Katz³, Nathan Karin¹, Amos Etzioni², Shimon Pollack⁴

Affiliations

¹ Department of Immunology, Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.
² Department of Immunology, Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel; Institute for Allergy, Immunology and AIDS, Rambam Health Care Campus, Haifa, Israel.
³ Institute for Allergy, Immunology and AIDS, Rambam Health Care Campus, Haifa, Israel.
⁴ Department of Immunology, Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel; Institute for Allergy, Immunology and AIDS, Rambam Health Care Campus, Haifa, Israel. Electronic address: [email protected].

PMID: 23791509
DOI: 10.1016/j.jaci.2013.04.018

No abstract available

Publication types

Case Reports
Letter
Research Support, Non-U.S. Gov't
Retracted Publication

MeSH terms

Candidiasis, Chronic Mucocutaneous / drug therapy*
Candidiasis, Chronic Mucocutaneous / genetics
Candidiasis, Chronic Mucocutaneous / immunology
Cytokines / immunology*
Female
Granulocyte Colony-Stimulating Factor / therapeutic use*
Humans
Middle Aged
STAT1 Transcription Factor / genetics
STAT3 Transcription Factor / genetics
Suppressor of Cytokine Signaling 1 Protein
Suppressor of Cytokine Signaling Proteins / genetics
Th17 Cells / immunology

Substances

Cytokines
SOCS1 protein, human
STAT1 Transcription Factor
STAT1 protein, human
STAT3 Transcription Factor
STAT3 protein, human
Suppressor of Cytokine Signaling 1 Protein
Suppressor of Cytokine Signaling Proteins
Granulocyte Colony-Stimulating Factor