The NLRP3 inflammasome activation in human or mouse cells, sensitivity causes puzzle

Protein Cell. 2013 Aug;4(8):565-8. doi: 10.1007/s13238-013-3905-0.

Authors

Hongbin Wang¹, Liming Mao, Guangxun Meng

Affiliation

¹ Unit of Innate Immunity, Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200025, China.

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Carrier Proteins / metabolism*
Caspase 1 / metabolism
Humans
Inflammasomes / metabolism*
Interleukin-1beta / metabolism
Lipopolysaccharides / toxicity
Mice
Monocytes / drug effects
Monocytes / immunology
Monocytes / metabolism
NLR Family, Pyrin Domain-Containing 3 Protein
Signal Transduction / drug effects

Substances

Carrier Proteins
Inflammasomes
Interleukin-1beta
Lipopolysaccharides
NLR Family, Pyrin Domain-Containing 3 Protein
NLRP3 protein, human
Caspase 1