One-step DNA-programmed growth of CpG conjugated silver nanoclusters: a potential platform for simultaneous enhanced immune response and cell imaging

Chem Commun (Camb). 2013 Aug 7;49(61):6918-20. doi: 10.1039/c3cc41972j.

Abstract

We designed a one-pot synthesis that allows CpG-functionalized AgNCs to be prepared, combining attractive features of enhanced immune response and intracellular imaging.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cell Line
  • Cytokines / drug effects*
  • Cytokines / immunology
  • DNA / chemistry
  • DNA / pharmacology*
  • Dinucleoside Phosphates / chemical synthesis
  • Dinucleoside Phosphates / chemistry
  • Dinucleoside Phosphates / pharmacology*
  • Humans
  • Metal Nanoparticles / chemistry*
  • Mice
  • Microscopy, Fluorescence
  • Particle Size
  • Silver / chemistry
  • Silver / pharmacology*
  • Surface Properties

Substances

  • Cytokines
  • Dinucleoside Phosphates
  • cytidylyl-3'-5'-guanosine
  • Silver
  • DNA