Diaminodiacid-based solid-phase synthesis of peptide disulfide bond mimics

Angew Chem Int Ed Engl. 2013 Sep 2;52(36):9558-62. doi: 10.1002/anie.201302197. Epub 2013 Jun 26.
No abstract available

Keywords: biological activity; cyclic peptides; disulfide bonds; solid-phase synthesis; β-hairpin structure.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acids, Diamino / chemistry*
  • Antimicrobial Cationic Peptides / chemistry
  • Antimicrobial Cationic Peptides / pharmacology
  • Bacteria / drug effects
  • Chromatography, High Pressure Liquid
  • Circular Dichroism
  • Cyclization
  • DNA-Binding Proteins / chemistry
  • DNA-Binding Proteins / pharmacology
  • Disulfides / chemical synthesis*
  • Disulfides / chemistry
  • Disulfides / pharmacology
  • Microbial Sensitivity Tests
  • Molecular Structure
  • Peptides / chemical synthesis*
  • Peptides / chemistry
  • Peptides / pharmacology
  • Peptides, Cyclic / chemistry
  • Peptides, Cyclic / pharmacology
  • Solid-Phase Synthesis Techniques

Substances

  • Amino Acids, Diamino
  • Antimicrobial Cationic Peptides
  • DNA-Binding Proteins
  • Disulfides
  • Peptides
  • Peptides, Cyclic
  • tachyplesin peptide, Tachypleus tridentatus