Objective: To study the relationship between serum folic acid and VB2 levels and esophageal cancer.
Method: The enzyme-linked immunosorbent assay was used to observe the serum folic acid and vitamin B2 levels of the 1:1:1 paired of 106 groups, which include 106 cases of esophageal cancer, 106 cases of esophageal precancerous lesions and 106 cases of normal control group.
Results: The levels of folic acid and VB2 in serum of esophageal cancer group and esophageal precancerous lesions group were significantly lower than normal control group (P<0.05), the level of folic acid in serum of esophageal cancer group was significantly lower than esophageal precancerous lesions group (P<0.05), but the difference of the serum VB2 of esophageal cancer group and esophageal precancerous lesions group was not statistically significant (P>0.05).
Conclusion: The folic acid and vitamin B2 deficiency has the relationship with the esophageal cancer occurrence and development.