Abstract
Testicular-sparing surgery may avoid definitive testosterone supplementation and preserve fertility in selected cases of men presenting with bilateral testicular tumours or in case of monorchidia. Testicular-sparing surgery may enable the conservation of both endocrine function and spermatogenesis in selected young men in order to preserve natural fatherhood, avoid definitive androgen replacement therapy and probably improve quality of life by reducing psychosexual consequences of anorchia. The tumorectomy must be followed by an external irradiation of the remaining testicle to eradicate testicular intratubular neoplasia revealed in 82% of cases after per-surgery biopsy. This approach concerns some rare indications. Dose level and technical consideration are still debated.
Keywords:
Bilateral testicular neoplasms; Conservative surgery; Germ cell tumour; Néoplasie testiculaire intraépithéliale; Radiotherapy; Radiothérapie; Testis; Testosterone; Testostérone; Tumeurs bilatérales testiculaires.
Copyright © 2013 Société française de radiothérapie oncologique (SFRO). Published by Elsevier SAS. All rights reserved.
MeSH terms
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Carcinoma in Situ / drug therapy
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Carcinoma in Situ / radiotherapy
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Chemotherapy, Adjuvant
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Clinical Trials as Topic / statistics & numerical data
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Combined Modality Therapy
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Hormone Replacement Therapy / psychology
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Humans
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Infertility, Male / prevention & control
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Infertility, Male / psychology
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Male
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Multicenter Studies as Topic / statistics & numerical data
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Neoplasms, Germ Cell and Embryonal / drug therapy
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Neoplasms, Germ Cell and Embryonal / psychology
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Neoplasms, Germ Cell and Embryonal / radiotherapy*
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Neoplasms, Germ Cell and Embryonal / surgery
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Neoplasms, Multiple Primary / drug therapy
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Neoplasms, Multiple Primary / psychology
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Neoplasms, Multiple Primary / radiotherapy
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Neoplasms, Multiple Primary / surgery
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Orchiectomy / adverse effects
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Orchiectomy / methods
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Orchiectomy / psychology
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Organ Sparing Treatments*
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Radiotherapy Dosage
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Radiotherapy, Adjuvant / methods*
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Radiotherapy, High-Energy / adverse effects
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Radiotherapy, High-Energy / methods*
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Randomized Controlled Trials as Topic / statistics & numerical data
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Stress, Psychological / etiology
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Stress, Psychological / prevention & control
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Testicular Neoplasms / drug therapy
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Testicular Neoplasms / psychology
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Testicular Neoplasms / radiotherapy*
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Testicular Neoplasms / surgery
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Testis / pathology
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Testis / radiation effects
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Testis / surgery
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Testosterone / therapeutic use
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Treatment Outcome