Neuroscience. Garbage truck of the brain

Science. 2013 Jun 28;340(6140):1529-30. doi: 10.1126/science.1240514.

Abstract

An intercellular “glymphatic” pathway clears cell waste from the brain and may reveal new targets for treating neurodegenerative diseases.

MeSH terms

  • Animals
  • Aquaporin 4 / metabolism*
  • Brain / physiopathology*
  • Cerebrospinal Fluid / metabolism
  • Extracellular Fluid / metabolism
  • Humans
  • Lymphatic Vessels / metabolism*
  • Mice
  • Neurodegenerative Diseases / cerebrospinal fluid
  • Neurodegenerative Diseases / physiopathology*
  • Neurodegenerative Diseases / therapy*
  • Neuroglia / metabolism*
  • Neurons / metabolism
  • Rats

Substances

  • Aquaporin 4