A case of generalized lichen nitidus successfully treated with narrow-band ultraviolet B treatment

Photodermatol Photoimmunol Photomed. 2013 Aug;29(4):215-7. doi: 10.1111/phpp.12037.

Abstract

Lichen nitidus (LN) is a rare skin disorder presenting with multiple, small and bright papules located on the chest, abdomen, penis glans and upper extremities. It usually presents with limited involvement; however, it can present as generalized involvement. There is no consensus on treatment. Corticosteroid, astemizole, phototherapy has been used; however, the results are controversial. A 15-year-old male with clinical and histopathological diagnosis of LN was treated with narrow-band ultraviolet B (NB-UVB). The lesions completely regressed with post-inflammatory hypopigmentation on the second month of the therapy (25 sessions). We believe that NB-UVB is an effective treatment on generalized LN.

Keywords: lichen nitidus; narrow-band UVB; phototherapy.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Adrenal Cortex Hormones / administration & dosage
  • Astemizole / administration & dosage*
  • Histamine H1 Antagonists, Non-Sedating / administration & dosage*
  • Humans
  • Lichen Nitidus / pathology
  • Lichen Nitidus / therapy*
  • Male
  • Time Factors
  • Ultraviolet Rays*
  • Ultraviolet Therapy*

Substances

  • Adrenal Cortex Hormones
  • Histamine H1 Antagonists, Non-Sedating
  • Astemizole