Conformal crystals are nonuniform structures created by a conformal transformation of regular two-dimensional lattices. We show that gradient-driven vortices interacting with a conformal pinning array exhibit substantially stronger pinning effects over a much larger range of field than found for random or periodic pinning arrangements. The pinning enhancement is partially due to matching of the critical flux gradient with the pinning gradient, but the preservation of local ordering in the conformally transformed hexagonal lattice and the arching arrangement of the pinning also play crucial roles. Our results can be generalized to a wide class of gradient-driven interacting particle systems such as colloids on optical trap arrays.