Purpose: To evaluate the clinical value of (18)F-fluorodeoxyglucose positron emission tomography (PET)/computed tomography (CT) in detection of primary lesions of bone metastases.
Methods: The PET/CT scans of 77 patients with bone metastases undetermined origin were retrospectively reviewed. The results of clinical information were collected.
Results: Forty-four suspected primary tumors were found on the PET/CT images in 77 patients of bone metastases, including 40 patients with the primary tumor confirmed, and 4 patients false-positive. In 37 patients, no primary lesions were detected, including one patient false-negative (signet-ring cell carcinoma). The sensitivity, specificity, and accuracy was 97.6%, 88.9%,and 93.5% respectively. The primary lesions of 51.9% patients could be diagnosed by PET/CT.
Conclusion: PET/CT is helpful in detecting the primary lesions of bone metastases.
Keywords: (18)F-FDG; Bone metastases; PET/CT; Primary lesions.
Copyright © 2013 Elsevier Inc. All rights reserved.