Intestinal GATA4 deficiency induces proximal fibroblast growth factor 15 expression and represses hepatic gluconeogenesis

J Hepatol. 2013 Nov;59(5):1147-9. doi: 10.1016/j.jhep.2013.07.003. Epub 2013 Jul 10.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Diet, High-Fat / adverse effects
  • Disease Models, Animal
  • Fatty Liver / etiology
  • Fatty Liver / metabolism*
  • Fibroblast Growth Factors / metabolism*
  • GATA4 Transcription Factor / deficiency*
  • GATA4 Transcription Factor / genetics
  • GATA4 Transcription Factor / metabolism
  • Glucagon-Like Peptide 1 / metabolism
  • Gluconeogenesis / physiology
  • Glucose / metabolism*
  • Intestinal Mucosa / metabolism*
  • Liver / metabolism*
  • Mice
  • Mice, Knockout

Substances

  • GATA4 Transcription Factor
  • Gata4 protein, mouse
  • fibroblast growth factor 15, mouse
  • Fibroblast Growth Factors
  • Glucagon-Like Peptide 1
  • Glucose