Photonic crystal encoded biomaterials microcarriers made from silica-hybrid photonic crystal beads are reported. The characteristic reflection peak originating from the physical periodic structure is used as the code of the microcarriers. They are stable during cell adhesion and culture on their surface. Based on this method, Different biomaterials are incorporated into different PCBs and used as encoded microcarriers for the multiplex evaluation of the interaction of cells and materials in a single culture experiment. These encoded microcarriers are ideal for multiplex bioevaluation of biomaterials or drug applications.
Keywords: cell culture; microcarriers; multiplex analysis; photonic crystal.
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