An ultrasensitive biosensor for DNA detection based on hybridization chain reaction coupled with the efficient quenching of a ruthenium complex to CdTe quantum dots

Chem Commun (Camb). 2013 Aug 28;49(67):7424-6. doi: 10.1039/c3cc42639d.

Abstract

A highly sensitive and selective DNA biosensor based on hybridization chain reaction is described, which combines CdTe quantum dots (QDs) and a ruthenium complex. Based on the variation of fluorescence signals of the CdTe QDs, the target DNA is determined.

Publication types

  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biosensing Techniques / methods*
  • Cadmium Compounds / chemistry*
  • Coordination Complexes / chemistry*
  • DNA / analysis*
  • DNA, Viral / analysis
  • Equipment Design
  • Papillomaviridae / genetics
  • Quantum Dots*
  • Ruthenium / chemistry*
  • Sensitivity and Specificity
  • Spectrometry, Fluorescence
  • Tellurium / chemistry*

Substances

  • Cadmium Compounds
  • Coordination Complexes
  • DNA, Viral
  • Ruthenium
  • DNA
  • Tellurium
  • cadmium telluride