Diffuse alveolar hemorrhage due to ketorolac tromethamine

Pharmacology. 2013;92(1-2):11-3. doi: 10.1159/000351844. Epub 2013 Jul 18.

Abstract

Drug-induced lung disease (DILD) is a common but frequently missed diagnosis. Therefore, a high index of clinical suspicion and familiarity with the clinical syndromes associated with DILD are important in making the diagnosis. Nonsteroidal anti-inflammatory drugs (NSAIDs) are one of the mostly commonly used classes of medications. NSAIDs are safe when used at prescribed doses. Side effects from use of NSAIDs are not uncommon and can affect almost every organ system in the body. NSAIDs are notorious for causing pulmonary toxicity, the common ones being bronchospasm and hypersensitivity reactions. Diffuse alveolar hemorrhage (DAH) secondary to NSAIDs is uncommon. Here, we report a case of DAH secondary to the use of ketorolac tromethamine.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anti-Inflammatory Agents, Non-Steroidal / adverse effects*
  • Hemorrhage / chemically induced*
  • Hemorrhage / diagnostic imaging
  • Humans
  • Ketorolac Tromethamine / adverse effects*
  • Lung Diseases / chemically induced*
  • Lung Diseases / diagnostic imaging
  • Male
  • Pulmonary Alveoli
  • Tomography, X-Ray Computed

Substances

  • Anti-Inflammatory Agents, Non-Steroidal
  • Ketorolac Tromethamine