A paucity of literature regarding strategies for injury prevention in children for mothers with substance abuse exists. Substance abuse propagates distractions such as inattention; therefore, these mothers should be targeted for injury prevention education. A quasi-experimental design compared the results of traditional classroom teaching with an innovative home hazard simulation activity to teach injury prevention to mothers recovering from substance abuse. Study results identified a need to employ multiple modalities when teaching injury prevention. Information obtained from this research suggests a need for continued study and adaptation of current teaching strategies for injury prevention education in other high-risk populations.